These are the settings I personally use while working in VFX studios. The layouts are just what I find the most efficient for the workflow of a matte painter, so it's up to you if you want to follow them. If you don't have your own setup you like, then start here and customize as you get to know what you like.

The keyboard shortcuts in this are the real game changer for matte painters, you'll be surprised how much you can speed up your work with these settings!